Crewe striker Chris Porter faces up to six weeks out after undergoing surgery on his ankle.
Crewe's leading scorer Chris Porter is likely to be out for six weeks with an ankle problem which requires an operation.
Crewe have completed the loan signings of Harry McKirdy from Aston Villa andDan Barlaser from Newcastle.
Peterborough have signed winger George Cooper from Crewe for an undisclosed fee.
Crewe manager David Artell was left to lament missed opportunities after seeing his side go down to a 1-0 defeat at Carlisle.
Crewe defender Perry Ng faces a four-match suspension after accepting a violent conduct charge.
David Artell says a trio of returning players can offer Crewe a boost in their relegation battle after the 2-0 win over Grimsby.
Shaun Derry was impressed after watching George Maris open the scoring after only 34 seconds in Cambridge's 3-1 victory over Crewe.