Tottenham's Champions League campaign ended with a whimper as they were swept aside by RB Leipzig in the second leg of their last-16 tie on Tuesday.
Jamie Vardy scored twice to bring his Premier League goal tally for the season up to 19 as Leicester City cruised to a 4-0 victory against Aston Villa.
Manchester United kept their top-four hopes very much alive with a 2-0 win over arch rivals Manchester City at Old Trafford.
Carlo Ancelotti endured a painful return to Chelsea as Frank Lampard's men put Everton to the sword at Stamford Bridge to move five points clear in fourth.
An improved second-half showing from Tottenham earned them a 1-1 draw at Burnley in what was a topsy-turvy late game in the Premier League.
Brighton moved a point further clear of the relegation zone after holding Wolves to a 0-0 draw at Molineux.
Newcastle United edged another step towards Premier League safety with a 1-0 win against ten-man Southampton at St Mary’s.
Watford came back down to earth after last Saturday’s incredible victory against Liverpool as they slumped to a 1-0 defeat at Crystal Palace.
Sheffield United moved into the Premier League’s top-six with a hard-fought 1-0 win against the bottom club Norwich City at Bramall Lane.
Alexandre Lacazette settled a lacklustre derby as Arsenal extended their unbeaten run in the Premier League to eight games with a 1-0 win against West Ham.
Liverpool returned to winning ways in the Premier League following last weekend’s drubbing at Watford with a 2-1 victory against Bournemouth.
Luke Shaw was on target and Odion Ighalo scored twice as Manchester United claimed a 3-0 FA Cup fifth round win at Derby County.
Norwich are through to the quarter-finals of the FA Cup for the first time since 1992 after Tim Krul guided them to a penalty shootout win over Tottenham.
Holders Manchester City eased into the last eight of the FA Cup as a Sergio Aguero goal secured a 1-0 victory at Sheffield Wednesday.
Ricardo Pereira scored the only goal of the game as Leicester City edged a 1-0 FA Cup fifth-round win at home to Birmingham City.
Substitute Billy Sharp was the hero for Sheffield United as they booked their place in the last eight of the FA Cup with a 2-1 extra-time win at Reading.
Newcastle are through to the quarter-finals of the FA Cup for the first time since 2006 after beating West Brom 3-2 at The Hawthorns on Tuesday.
Goals from Willian and Ross Barkley made the difference as Chelsea beat Liverpool 2-0 in the fifth-round of the FA Cup.
Arsenal eased into the last eight of the FA Cup as they defeated League One promotion hopefuls Portsmouth 2-0 at Fratton Park.
Manchester City claimed the EFL Cup for the third year in a row with a 2-1 victory over Aston Villa at Wembley Stadium.
Wolves twice came from behind to secure a 3-2 victory at Tottenham Hotspur which handed them a huge boost in their bid to secure a top-four finish.